Dr. Frank Biedermann

Dr. Frank Biedermann is the group leader of the Emmy Noether research entity at the Insitute of Nanotechnology.Dr. Frank Biedermann - Group Leader


Phone: 0049-(0)721/608-26341

E-Mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

Office: 0-207

Hermann-von-Helmholtz-Platz 1

76344 Eggenstein-Leopoldshafen






  • 09/2016 – now: Emmy Noether fellow at the Karlsruhe Institute for Technology (KIT), Institute for Nanotechnology (INT),

  • 12/2014 – 08/2016: Postdoc, Karlsruhe Institute for Technology (KIT), Institute for Nanotechnology (INT), with Prof. Dr. L. De Cola

  • 12/2013 – 11/2014: Postdoc, Institut de Science et d'Ingénierie Supramoléculaires, Strasbourg, with Prof. Dr. L. De Cola

  • 10/2012 – 11/2013: Postdoc, Jacobs University Bremen, with Prof. Dr. W. M. Nau

  • 10/2008 – 10/2012: PhD in Chemistry, University of Cambridge, UK, with Dr. O. A. Scherman

  • 10/2007 – 06/2008 Part III course in Chemistry, University of Cambridge, UK

  • 10/2006 – 06/2007 Part-time studies Physics (1. and 2. semester), TU Kaiserslautern

  • 10/2004 – 08/2007 B. Sc., Universität Leipzig


Selected Publications

  1. Cavitation energies can outperform dispersion interactions S. He, F. Biedermann, N. Vankova, L. Zhechkov, T. Heine, R. E. Hoffman, A. De Simone, T. T. Duignan, W. M. Nau, Nat. Chem. 2018, 10, 1252-1257.
  2. Programmable and Sequence-Selective Supramolecular Assembly of Two Different Chromophores along DNA Templates R. Hofsäß, S. Sinn, F. Biedermann, H.-A. Wagenknecht, Chem. Eur. J. 2018, 24, 16257-16261.
  3. Platinum Complex Assemblies as Luminescent Probes and Tags for Drugs and Toxins in Water S. Sinn, F. Biedermann*, L. De Cola*, Chem. Eur. J. 2017231965–1971. 
  4. Experimental Binding Energies in Supramolecular Complexes  F. Biedermann*, H.-J. Schneider*, Chem. Rev. 2016116, 5216-5300. 
  5. Nanomolar Binding of Steroids to Cucurbit[n]urils: Selectivity and Applications  A. I. Lazar; F. Biedermann*; K. R. Mustafina; K. I. Assaf; A. Hennig; W. M. Nau J. Am. Chem. Soc. 2016138, 13022-13029. (Highlighted in local newspaper) 
  6. Associative chemosensing by fluorescent macrocycle–dye complexes–a versatile enzyme assay platform beyond indicator displacement F. Biedermann*, D. Hathazi, W.M. Nau*, Chem. Commun201551, 4977-4980. 
  7. The Hydrophobic Effect Revisited—Studies with Supramolecular Complexes Imply High?Energy Water as a Noncovalent Driving Force F. Biedermann*, W.M. Nau*, H.-J. Schneider*, Angew. Chem. Int. Ed2014, 53, 11158–11171. 
  8. Noncovalent chirality sensing ensembles for the detection and reaction monitoring of amino acids, peptides, proteins, and aromatic Drugs F. Biedermann*, W.M. Nau*, Angew. Chem. Int. Ed. 2014, 53, 5694-5699. 
  9. Mechanically strong, fluorescent hydrogels from zwitterionic, fully ?-conjugated polymers  E. Elmalem, Frank Biedermann*, M. R. J. Scherer, A. Koutsioubas, C. Toprakcioglu, G. Biffi, W. T. S. Huck*, Chem Commun2014, 50, 8930–8933. 
  10. Cucurbit[8]uril and blue-box: high-energy water release overwhelms electrostatic interactions F. Biedermann*, M. Vendruscolo, O. A. Scherman, A. De Simone, W. M. Nau, J. Am. Chem. Soc., 2013, 135, 14879-14888. 
  11. Release of high-energy water as an essential driving force for the high-affinity binding of cucurbit[n]urils  F. Biedermann, V. D. Uzunova, O. A. Scherman, W. M. Nau, A. De Simone, J. Am. Chem. Soc.2012, 134, 15318-15323. 
  12. Strongly fluorescent, switchable perylene bis (diimide) host–guest complexes with cucurbit[8]uril in water  F. Biedermann, E. Elmalem, I. Ghosh, W. M. Nau, O. A. Scherman, Angew. Chem. Int. Ed.2012 51, 7739-7743.



  • Highly selective artificial neurotransmitter receptors (2015)

  • Chiralitätsdetektion mit achiralen Wirt-Gast Sensoren (2014)

  • Cucurbituril-based hydrogels (2013)