Dr. Stephan Sinn

Dr. Stephan Sinn deals with the development of fluorescence based assays for the detection of biological relevant analytes.

Furthermore, he develops physico chemical models for supramolecular interactions and is responsible for the development of the cheminformatics platform SupraBank.Dr. Stephan Sinn - PostDoc

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Phone: 0049-(0)721/608-26883

E-Mail: This email address is being protected from spambots. You need JavaScript enabled to view it.  

Office: 0-206

Hermann-von-Helmholtz-Platz 1

76344 Eggenstein-Leopoldshafen







  • Since 2017               PostDoc at the Instituet of Nanotechnology (INT) of the Karlsruhe Institute of Technology (KIT), Germany                              

                                     (Emmy Noether Group of Dr. Frank Biedermann)

  • 2013 – 2017             PhD thesis at the Institut de Science et d'Ingénierie Supramoléculaires of the Université de Strasbourg, France 

                                     (Prof. Luisa De Cola, Prof. Jean-Marie Lehn)

  • 2007 – 2012             University studies and diploma thesis in chemistry at the Friedrich-Schiller-Universität Jena, Germany

                                     (Prof. Ulrich S. Schubert)


Selected Publications 

  • Fluorescent Nanozeolite Receptors for the Highly Selective and Sensitive Detection of Neurotransmitters in Water and Biofluids; L. M. Grimm, S. Sinn, M. Krstic, E. D'Este, I. Sonntag, E. A. Prasetyanto, T. Kuner, W. Wenzel, L. De Cola, F. Biedermann, Adv. Mater 2021, 2104614.
  • Fluorescence detected circular dichroism (FDCD) for supramolecular host-guest complexesA. Prabodh, Y. Wang, S. Sinn, P. Albertini, C. Spies, E. Spuling, L.-P. Yang, W. Jiang, S. Bräse, F. Biedermann, Chem. Sci. 2021Avance Article.
  • Teaching indicators to unravel the kinetic features of host-guest inclusion complexes, A. Prabodh, S.Sinn, L. Grimm, Z. Miskolczy, M. Megyesi, L. Biczók, S. Bräse, F. Biedermann*, Chem. Commun., 2020 , 56, 12327-12330.
    This publication was featured as inside front cover in Chemical Communications.

  • Teaching old indicators even more tricks: binding affinity measurements with the guest-displacement assay (GDA); S. Sinn, J. Krämer, F. Biedermann*, Chem. Commun., 2020, 56, 6620-6623.
    This publication was featured as front cover in Chemical Communications.

  • Rational Design and Implementation of a Cucurbit [8] uril-based Indicator-Displacement Assay for Application in Blood Serum; S. Sinn, E. Spuling, S. Bräse, F. Biedermann, Chem. Sci., 2019, 10, 6584-6593.
    This publication was featured as front cover in Chemical Science

  • Charge transport enhancement in supramolecular oligothiophene assemblies using Pt(II) centers as a guide; R. Carretero, Y. Atoini, T. Han, A. Operamolla, S. Ippolito, C. Valentini, S. Carrara, S. Sinn, E. A. Prasetyanto, T. Heiser, P. Samorì, G. Farinola, L. De Cola, J. Mater. Chem. A, 2019, 7, 16777-16784.

  • Programmable and Sequence-Selective Supramolecular Assembly of Two Different Chromophores along DNA Templates; R. Hofsäß, S. Sinn, F. Biedermann, H.A. Wagenknecht, Chemistry–A European Journal, 2018, 24 (61), 16257-16261

  • Chemical Sensors Based on Cucurbit[n]uril Macrocycles; S. Sinn, F. Biedermann, Israel Journal of Chemistry, 2018, 58 (3-4), 357-412.

  • Templated Formation of Luminescent Virus-like Particles by Tailor-Made Pt (II) Amphiphiles; S. Sinn, L. Yang, F. Biedermann, D. Wang, C. Kübel, J. Cornelissen, L. De Cola, JACS, 2018, 140 (6), 2355-2362.

  • Pyrazole[4,3-h]quinoline ligand based iridium(III) complexes for electrochemiluminescence; Hsu, E. Longhi, S. Sinn, C. S. Hawes, D. C. Young, P. E. Kruger, L. De Cola*, Chem. Asian J. 2017, 12 (13), 1649-1658.

  • Platinum Complex Assemblies as Luminescent Probes and Tags for Drugs and Toxins in Water; Sinn, F. Biedermann, L. De Cola*, Chem. Eur. J. 2017, 23, 1965-1971.

  • Stabilisation effects of phosphane ligands in the homogeneous approach of sunlight induced hydrogen production; Strabler, S. Sinn, R. Pehn, J. Pann, J. Dutzler, W. Viertl, J. Prock, K. Ehrmann, A. Weninger, H. Kopacka, L. De Cola* and P. Brueggeller*, Faraday Discuss., 2017.

  • Discrete polygonal supramolecular architectures of isocytosine-based Pt(ii) complexes at the solution/graphite interface; El Garah, S. Sinn, A. Dianat, A. Santana-Bonilla, R. Gutierrez, L. De Cola, G. Cuniberti, A. Ciesielski and P. Samori*, Chem. Commun., 2016, 52, 11163-11166.

  • A Ratiometric Luminescent Switch Based on Platinum Complexes Tethered to a Crown-Ether Scaffold; Sinn, F. Biedermann, M. Vishe, A. Aliprandi, C. Besnard, J. Lacour*and L. De Cola*, ChemPhysChem, 2016, 17, 1829-1834.

  • A heteroleptic bis(tridentate) ruthenium(II) platform featuring an anionic 1,2,3-triazolate-based ligand for application in the dye-sensitized solar cell; Sinn, B. Schulze, C. Friebe, D. G. Brown, M. Jager, J. Kubel, B. Dietzek, C. P. Berlinguette and U. S. Schubert*, Inorg. Chem., 2014, 53, 1637-1645.

  • Physicochemical Analysis of Ruthenium(II) Sensitizers of 1,2,3-Triazole-Derived Mesoionic Carbene and Cyclometalating Ligands; Sinn, B. Schulze, C. Friebe, D. G. Brown, M. Jager, E. Altuntas, J. Kubel, O. Guntner, C. P. Berlinguette, B. Dietzek and U. S. Schubert*, Inorg. Chem., 2014, 53, 2083-2095.

  • Ruthenium(II) photosensitizers of tridentate click-derived cyclometalating ligands: a joint experimental and computational study; Schulze, D. Escudero, C. Friebe, R. Siebert, H. Gorls, S. Sinn, M. Thomas, S. Mai, J. Popp,* B. Dietzek, L. Gonzalez* and U. S. Schubert*, Chem. Eur. J., 2012, 18, 4010-4025.
    This publication was featured as front cover in Chemistry - A European Journal